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1. Profile and contact information

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By checking this box, you understand and agree that this site requires that you submit personal health and contact information in order to enroll yourself or a patient for whom you are the caregiver in the PANCREAZE Engage Program. As the individual enrolling in the Program, by clicking on “ACCEPT AND CONTINUE” below, you are confirming that you are 18 years of age or older and read and understand the TERMS OF USE and the PRIVACY POLICY of VIVUS, that you understand that submission of personal health and contact information is required for participation in the Program, that you authorize VIVUS or its designee to utilize the personal health and contact information provided by you for the purpose of providing you with the benefits of the Program and otherwise fulfilling the objectives of the Program and you are freely providing this information to meet eligibility criteria for participation. If you are a caregiver to a patient, you are representing that you are duly authorized to provide this information, are freely providing it, and are authorized to receive the benefits of the Program on behalf of the patient. Program benefits include the fulfillment of costs savings for prescriptions through the use of the PANCREAZE Engage Savings Card and monthly discounts on nutritional supplements and other products or materials via the VIVUS Health Store. You agree that such benefits can be sent to you via direct mail or email, or through telephone communication. By registering for the PANCREAZE Engage program, and by using this site, you are authorizing VIVUS or its designee to contact you by telephone, direct mail or email in order to receive the benefits and verify continued eligibility. As the individual enrolling the patient or as the patient, you agree that you are responsible for maintaining the confidentiality of the User Name and Password required for access to this site. For more information about VIVUS’ privacy practices, please view the PRIVACY POLICY.

I understand that by clicking the Accept and Continue button below, I am consenting electronically and providing legal authorization for VIVUS, including any affiliates, subcontractors, and/or agents of VIVUS (such as vendors operating the PANCREAZE Engage Patient Savings Program) to use and share the personal health and contact information I provide for the purposes described within the above authorization.

Optional: SMS/Text Messages (NEW) Please note that messages will be delivered from the sender (669) 303-7737.

I agree to receive special offers and monthly discount codes from PANCREAZE Engage.

I agree to receive important updates and messages related to my account from PANCREAZE Engage.

By checking one or both of these boxes, I understand and agree to receive SMS/text messages from PANCREAZE Engage in connection with the PANCREAZE Engage Program, as described in the TERMS OF USE and PRIVACY POLICY, at the number I provide. Messages may include special offers, important program updates, and messages related to my account.

I acknowledge that I can choose to stop receiving text messages at any time by texting "STOP" to (669) 303-7737. To rejoin the SMS service, I can edit my profile to opt back into the program. If experiencing issues with the messaging program, I can reply with the keyword “HELP” for help. Message frequency varies. Message and data rates may apply. Participating carriers: all U.S. based carriers.

I understand that I am not required to agree to receive text messages as a condition of enrolling in the PANCREAZE Engage program.

 

 
By clicking on the Accept and Continue button below, you agree to the VIVUS TERMS OF USE, including its arbitration provisions, and PRIVACY POLICY.

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What is PANCREAZE?

PANCREAZE is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes.

Important Safety Information

What is the most important information I should know about PANCREAZE?​

PANCREAZE may increase your chance of having a serious, rare bowel disorder called fibrosing colonopathy that may require surgery. Fibrosing colonopathy has been reported with high dosages of pancreatic enzyme products, usually with use over a prolonged period of time and in pediatric patients with cystic fibrosis. Colonic stricture has been reported in pediatric patients less than 12 years of age.

Take PANCREAZE exactly as prescribed by your doctor. Do not take more or less PANCREAZE than directed by your doctor.

Call your doctor right away if you have any unusual or severe stomach area (abdominal) pain, bloating, trouble passing stool (having bowel movements), nausea, vomiting, or diarrhea.

What should I tell my doctor before taking PANCREAZE?

Tell your doctor if you:

  • are allergic to pork (pig) products
  • have a history of blockage of your intestines, or scarring or thickening of your bowel wall (fibrosing colonopathy)
  • have gout, kidney disease, or high blood uric acid (hyperuricemia)
  • have trouble swallowing capsules
  • have any other medical condition
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

What are the possible side effects of PANCREAZE?

PANCREAZE may cause serious side effects, including:

  • A rare bowel disorder called fibrosing colonopathy
  • Irritation of the inside of your mouth. This can happen if PANCREAZE is not swallowed completely
  • Increase in blood uric acid levels. This may cause worsening of swollen, painful joints (gout) caused by an increase in your blood uric acid levels. This may occur if you have gout or renal impairment. Contact your healthcare provider if you experience pain, stiffness, redness or swelling of your joints.
  • Allergic reactions including trouble with breathing, skin rashes, or swollen lips
  • PANCREAZE and other pancreatic enzyme products are made from the pancreas of pigs, the same pigs people eat as pork. These pigs may carry viruses. Although it has never been reported, it may be possible for a person to get a viral infection from taking pancreatic enzyme products that come from pigs.

The most common side effects include pain in your stomach (abdominal pain) and gas.

These are not all the side effects of PANCREAZE. Talk to your doctor about any side effect that bothers you or does not go away. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to VIVUS LLC at 1-888-998-4887.

How do I take PANCREAZE?

  • Take PANCREAZE with meals or snacks.
  • Swallow capsules whole.
  • For adult and pediatric patients unable to swallow intact capsules, the capsule contents may be sprinkled on a small amount of soft acidic food with a pH of 4.5 or less (e.g., applesauce).
  • For pediatric patients birth to 12 months of age, PANCREAZE capsules can also be opened, and the capsule contents sprinkled directly into the infant’s mouth.
  • Consume sufficient liquids (juice, water, breast milk, or formula) and visually inspect an infant’s mouth to ensure complete swallowing of PANCREAZE capsules or capsule contents.
  • Do not crush or chew PANCREAZE capsules or capsule contents.

Please read the PANCREAZE Medication Guide and PANCREAZE Product Information and discuss any questions you have with your doctor.

References: 1. Pezilli R, et al. Exocrine pancreatic insufficiency in adults: A shared position statement of the Italian association for the study of the pancreas. World J Gastroenterol. 2013;19 (44):7930-7946. 2. Cleveland Clinic. (n.d.). Exocrine Pancreatic Insufficiency (EPI). Retrieved from https://my.clevelandclinic.org/health/diseases/21577-exocrine-pancreatic-insufficiency-epi 3. Othman MO, et al. Introduction and practical approach to exocrine pancreatic insufficiency for the practicing clinician. Int J Clin Pract. 2018;72:e13066.

Important Safety Information

PANCREAZE may increase your chance of having a serious, rare bowel disorder called fibrosing colonopathy that may require surgery. Fibrosing colonopathy has been reported with high dosages of pancreatic enzyme products, usually with use over a prolonged period of time and in pediatric patients with cystic fibrosis. Colonic stricture has been reported in pediatric patients less than 12 years of age.

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